Sedefkar-mother of pearl artisan Fatma Ayran had started her training at the age of 16. She received her training from the artisan Ahmet Sezen and worked on numerous restoration projects of Hagia Sofia and Süleymaniye mosque. In 2010, Ayran opened her own workshop in Kucukayasofya, Istanbul. She has had several exhibitions at the Istanbul Chamber of Commerce in 2008, 2009, and 2010, and at the Uskudar Katibim Handicrafts in 2009 and 2010.

She is among the few artists who worked with the Eser-i İstanbul style and she is the only female artist. She designs and produces every detail by herself. She uses all natural materials like silver, pearl, rose tree, ebony tree, horn. Currently, Ayran continues to work at her workshop.